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Thank you so much for linking these steps together and how data in bioinformatics helps to reveal bigger truths in biology. Excited to read more papers in my field.

So well explained about Bioinformatics analysis and the relevance of writing script that is in high demand in top bioinformatics labs. Makes me excited about Bioinformatics software. Thank you

I am a Medical Laboratory Scientist and I have been interested in databases and software for a while now. Strongly considering a career upgrade into bioinformatics. I already started learning Python and will dive into stats once I develop a solid grasp of programming.

You discuss how bioinformatic skills are transferrable to the data science and ML space, but does it also apply vice-versa?

The most important reason for me to choose bioinformatics over wet lab biology is that I hate wet lab work with a passion

Hi, can you explain installation and download ? I can't get the same interface for work.thanks

Helpful video. I studied biochemistry and mathematics in undergrad, then went on to be an AP Biology teacher for 5 years. I am looking for a career change and bioinformatics is where I ultimately want to go. This video has given me some nice clear steps on some of the initial skills to begin to develop, thanks!

I have a lot of understanding of biology and I LOVE biology and genetics. Any time I see an ATCG or AUCG I get overwhelmed with excitement. My undergrad is in Evolutionary Anthropology and Biology, but I have been learning Python and brushing up on my statistics. I recently applied to ASU in hopes of earning a master's in Biological Data Science and then working on my PhD in Biomedical Informatics with a focus on translational informatics. Whether I can pull it off or not is unknown, but that is my goal. I am late in the game and actually have my MBA in IT with a data science and business analytics emphasis, but I am a lover of science and wish I would have stayed with it. So by the time I am 47 I will have my PhD if I can pull this off. Not to bad... right? Or am I crazy for this and it is a bad idea? I don't know.

hey i cant open the link provided by 1000 vcf genomes! it says can't connect??

amazing information. thanks for the video it clarifies a lot of things for me!

I just finshed my undergrad in biologly and did a bioinformatics project for my capstone. Loved it so much decided to do my masters in bioinformatics at the University of Maryland Global in the fall.

I actually for my Bachelors thesis designed a drug, and I want to pursue Masters in Bioinformatics and so I recently took a workshop on Bioinformatics. but the problem is I dont have any knowledge on coding and so while Drug designing I thought I can easily make a career in this (which I'm 90% sure I can, but in Pakistan, This field is under developing [like every other field]) and because I don't know where to start. Would you please help me with where should I should i get started from? (PYTHON OR R language) thanks for reading.

Is there a Google Health team in France? I am an international student in France studying medicine, and I hold a bachelor's degree in computer science. I have already completed an internship in a research lab focused on computer vision (PyTorch, U-Net, AUNet) applied to biology, and I am very interested in having an internship experience with the Google team next summer (2025). What advice can you give me ?

I'm about a year into my PhD in molecular microbiology... I'm mainly in the lab but my thesis will involve bioinformatics and in silico stuff so I need to learn command-line and feeling incredibly overwhelmed

I am one semester into my Bioinformatics MS, with a B.S. in Biological sciences. I was an RA in a microbiology lab, and am currently working in a cognitive neuroscience lab. I would say I am definitely strongest in the biology section, with a good amount of experience (for my age of course) in a variety of labs. My weakest point is statistics, which I never took a class in throughout my entire academic career. I will be taking it next semester, along with a computational methods course. I am excited to hear more.

Can medical student specialist in bioinformatic ?

This video is very helpful. Thank you !

what is the purpose of this plot? how you can use this plot to come up with solutions for a disease?

I am a biologist looking to achieve bioinformatics skills in the area of genomics and functional genomics.

I am computer science major with an AAS in Mathematics. I just learned about bioinformatics. The school I am attending for BS degree in computer science has an option to minor in bioinformatics.

Thanks a lot, you have been very clear. Bravo

But I came from chemistry field.

Hey how's it going guys, I'm a veteran that's been out of the service for many years and used his GI bill foolishly to get an associates only, having swaping majors so many times, fast forward years later I get a temp job now salary at a bio tech company, and love everything about genetics and machine learning, and taking bioinformatics and applying that knowledge to ai, so my question finally is I have an associates and wish to get my under grad what will be a straight shot pathway to bioinformatics, or more advantageous for machine learning and genetics, and bioinformatics in terms of undergrad, and what areas will I need to focus on! Loaded question possibly but hope to hear from you!

I just graduated with a BSc in Biochemistry and Chemistry. I am fascinatd about mixing physical and biological sciences with programming. I am actually learning how to code(in JavaScript but I will definitely do python) since I have found a job yet. I just want to ask about job opportunities? Do bioinformatists completely work outside the lab? The requirements seem fair me.

I try to cite each tool that I use for which the creator(s) of the tool would benefit from (or care about) a citation. If it's Microsoft Word, for example, I obviously would not cite it. But anything for which there is a paper, I try to cite it. I have never been asked to reduce my number of citations. I nearly always publish in online-only journals, so it has not been an issue for me.

When it comes to citing tools not mentioned in the methods, the Cell Press journals have this concept of STAR methods (Structured, Transparent, Accessible Reporting), which includes a Key Resources Table where you can list the software/algorithms that you used. I've seen papers use this section to credit tools like samtools and IGV. I think this is a good approach.

00:00 Introduction 00:41 Examples of well-maintained software 08:23 Maintenance after leaving 13:45 Web apps vs CLI 26:02 Running code client-side 33:50 Expected support duration 41:03 Other technical lessons 48:15 Fixing the current system

A software engineer researcher here. I work at a commercial metabolomics research lab that's a also a research lab at a university. And I do exactly what you were talking about around 57:00. I build projects (mostly webapps and databases and SaaS like services and bio related algorithms) and teach and mentor more junior "bio software engineers" who are mainly undergrad and grad students at the bio department, while they work on and maintain the older projects and learn at the same time. Edit: typo

I think webapps should be made as separate modules so that many CLIs can produce generic and simple outputs that are compatible with the UI module. But bioinformticians aren't good engineers, especially early on, when they create their most influential tools... 😅 Also, you could still dockerize your old tools today!

A well-balanced view on the subject.

Well this is awkward. I was just searching around for possible ideas for a field in which to pursue a masters degree. I have a bachelor's in computer science and a bachelor's in biology, because those were the two biggest educational interests I wanted to pursue in my life. Until just this moment, I had no idea bioinfomatics was a thing.

I’ve just got into bioinformatics PhD. Got my first meeting today. Feeling this is a new step in my life. Im so excited

I just came across your video while search for a way to get started in the bioinformatics field with no support to plug into, i must this is like a compass i really appreciate your effort. I would really appreciate it if you could help with links to learn this python in details, if possible free links to study the python programming and other areas as well once again thank you so much look forward to more videos

I'm a CS major, still in college. I always was interested in Biology, but ended up switching my career paths at the last moment in high school because I liked doing CS more. Since then I have been trying to find a middle ground where I can have my feet planted in both the domains. I'll check out some of your videos and see if the field is still accessible as an outsider or do you first need a good foundation in biology (beyond high school). I'm ready to learn more biology, it's just more exciting stuff to try!

hello. I'm a person with a biological research background in field of wet lab molecular biology (i'm a student now) like so many others, I made a mistake and starting think about how to develop bikes insted of how to use it. I didn't need to write a scripts and use programs and tools. how I can get to the level of scripting and deep understanding of my work, analyse data that i have received in my lab experiments? if not a bioinformatics course, maybe just programming in python, R? what I can do to improve my lab practice with a bioinformatic expirience, what kind of expirience it should be?

I have a BA in biology with some computer science courses. Im interested in bioinformatics as a way of processing my own data. Currently i am only learning and dont have data to analyze that would benefit from the sequence analysis techniques ive learned from the biostar handbook. I am mostly interested in wetlab work but am interested in seeing how i could maybe do bioinformatics as a work from home job.

Good job teaching, Maria. Making things easy is the hallmark of education in my book. Thank you!

In this age, why do we still need to learn programming language?

I am a final year undergraduate student i want to learn the basics of bioinformatics, kindly provide direction

Thank you and good for me i found this channel. I just started my journey in bioinformatics from one of my lecturers so things haven't become too complex, but i would look to see more videos on computer part of bioinformatics Thank you

Hi, I'm in my 1st year of MS in Applied Mathematics. I have experience with ML with Python. Also, I have been studying GNNs for my research topic. I have always wanted to work in the Bio-related areas field but don't have the knowledge of Biology. I'm thinking of getting into Bioinformatics where maybe I can use the GNNs in some way. Any advice for me?

Hi, I am glad I found this channel. I am finishing my first year of a MS in Bioinformatics. I have a BS in Biology and kind of self-learned r and some python. I look forward to do a PhD in Bioinformatics or a related research topic. I would like to keep on track on this channels to see my career options and development in future (Industry VS ACADEMIA) thanks for this video and sharing your knowledge and experience I look forward to see more.

Is there a trial version for the circa software? I don´t know if thsi siftware fits to my data, som I would love to have a trial version. If it fits, I would buy it definitley.

very informative video , i most certainly got a handfull

I am a combined undergraduate senior / first year master's student in chemical engineering. In my research I have mainly focus doing models and simulations of very small particle systems, but recently I have been wanting to learn a bit more about biology so I applied to bioinformatic internships this summer and actually got one. Bioinformatics seems like a really cool field so I want to see if this is the potential field that I want to work and maybe go to graduate school for.

thanks for the videoooo

Data Scientist here but want to learning more on the bioinformatic things , and tried to have my master on this

Hey maria, could you recommend a laptop for bioinformatics phd ? Thanks !

U weet niet alleem genetica, maar ook het UNIX/LINUX commandlijn, meisje!🙂🙂👍 Dit is raar in onze dagen.